药物信息为5.4% NephrAmine (Essential Amino Acid Injection) (B. Braun Medical Inc.): DESCRIPTION

5.4% NephrAmine (Essential Amino Acid Injection) is a sterile, nonpyrogenic solution containing crystalline essential amino acids plus histidine. Each 250 mL unit provides Rose's recommended daily intake of essential amino acidsRose WC: The sequence of events leading to the establishment of the amino acid needs of man. Am J Public Health; 1968: 58 (11):2020–2027. plus 625 mg of histidine, considered essential for uremics. The total nitrogen content of a 250 mL unit is approximately 1.6 grams (10 g of protein equivalent) in 14 grams of amino acids. All amino acids designated USP are the "L" isomer.

Each 100 mL contains:

Histidine USPHistidine is considered an essential amino acid in uremic patients...............................................0.25 g

Isoleucine USP..............................................0.56 g

Leucine USP.................................................0.88 g

Lysine...........................................................0.64 g

(added as Lysine Acetate USP....................0.90 g)

Methionine USP............................................0.88 g

Phenylalanine USP.........................................0.88 g

Threonine USP..............................................0.40 g

Tryptophan USP...........................................0.20 g

Valine USP....................................................0.64 g

Cysteine....................................................<0.014 g

(as Cysteine HCl•H₂O USP....................<0.020 g)

Sodium Bisulfite (as an antioxidant)..............<0.05 g

Water for Injection USP......................................qs

pH adjusted with Sodium Hydroxide NF as required.

pH: 6.5 (6.0–7.0); Calculated Osmolarity: 435 mOsmol/liter

Total Nitrogen: Approx. 0.65 g/100 mL

Concentration of Electrolytes (mEq/liter): Sodium 5

Chloride <3; Acetate Approx. 44