药物信息为CLARITHROMYCIN (KAISER FOUNDATION HOSPITALS): DESCRIPTION
- DESCRIPTION
- CLINICAL PHARMACOLOGY
- MICROBIOLOGY
- INDICATIONS AND USAGE
- CONTRAINDICATIONS
- WARNINGS
- PRECAUTIONS
- Information For Patients
- Drug Interactions
- Carcinogenesis, Mutagenesis, Impairment of Fertility
- Pregnancy
- Nursing Mothers
- Geriatric Use
- ADVERSE REACTIONS
- OVERDOSAGE
- DOSAGE AND ADMINISTRATION
- HOW SUPPLIED
- CLINICAL STUDIES
- ANIMAL PHARMACOLOGY AND TOXICOLOGY
- REFERENCES
- 外部链接相关的CLARITHROMYCIN (KAISER FOUNDATION HOSPITALS)
Clarithromycin is a semi-synthetic macrolide antibiotic. Chemically, it is 6-0-methylerythromycin. The molecular formula is C38H69NO13, and the molecular weight is 747.96. The structural formula is:
Clarithromycin is a white to off-white crystalline powder. It is soluble in acetone, slightly soluble inmethanol, ethanol, and acetonitrile, and practically insoluble in water.Clarithromycin is available as immediate-release tablets, extended-release tablets, and granules for oral suspension.Each yellow oval film-coated immediate-release tablet of Clarithromycin Tablets, USP contains 250mg or 500mg of clarithromycin and the following inactive ingredients:250mg tablets: hypromellose, hydroxypropyl cellulose, croscarmellose sodium, D and C Yellow No. 10, FD and C Blue No. 1, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, propylene glycol, silicon dioxide, sorbic acid, sorbitan monooleate, stearic acid, talc, titanium dioxide,and vanillin.500 mg tablets: hypromellose, hydroxypropyl cellulose, colloidal silicon dioxide, croscarmellosesodium, D and C Yellow No. 10, magnesium stearate, microcrystalline cellulose, povidone, propylene glycol, sorbic acid, sorbitan monooleate, titanium dioxide, and vanillin.Each yellow oval film-coated BIAXIN XL tablet (clarithromycin extended-release tablets) contains 500mg of clarithromycin and the following inactive ingredients: cellulosic polymers, D and C Yellow No. 10, lactose monohydrate, magnesium stearate, propylene glycol, sorbic acid, sorbitan monooleate, talc, titanium dioxide, and vanillin.After constitution, each 5 mL of Clarithromycin for Oral Suspension, USP contains 125mg or 250mg of clarithromycin. Each bottle of Clarithromycin for Oral Suspension, USP contains 1250mg (50 mL size), 2500 mg (50 and 100 mL sizes) or 5000 mg (100 mL size) of clarithromycin and the following inactive ingredients: carbomer, castor oil, citric acid, hypromellose phthalate, maltodextrin, potassium sorbate, povidone, silicon dioxide, sucrose, xanthan gum, titanium dioxide and fruit punch flavor.
- Drug Information Provided by National Library of Medicine (NLM).
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