药物信息为DARAPRIM (pyrimethamine) 25-mg Scored Tablets (GlaxoSmithKline): REFERENCES

• Eyles DE, Coleman N. Synergistic effect of sulfadiazine and Daraprim against experimental toxoplasmosis in the mouse. Antibiot Chemother. 1953;3:483-490.
• Jacobs L, Melton ML, Kaufman HE. Treatment of experimental ocular toxoplasmosis. Arch Ophthalmol. 1964;71:111-118.
• Jim RTS, Elizaga FV. Development of chronic granulocytic leukemia in a patient treated with pyrimethamine. Hawaii Med J. 1977;36:173-176.
• Sadoff L. Antimalarial drugs and Burkitt’s lymphoma. Lancet. 1973;2:1262-1263.
• Bahna L. Pyrimethamine. LARC Monogr Eval Carcinog Risk Chem. 1977;13:233-242.
• Clive D, Johnson KO, Spector JKS, et al. Validation and characterization of the L5178Y/TK +/- mouse lymphoma mutagen assay system. Mut Res. 1979;59:61-108.

Manufactured by

DSM Pharmaceuticals, Inc.

Greenville, NC 27834 for

GlaxoSmithKline

Research Triangle Park, NC 27709

©2003, GlaxoSmithKline. All rights reserved.

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