药物信息为DILTIA XT brand of DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE CAPSULES, USP (ONCE-A-DAY-DOSAGE) (Watson Pharma, Inc.): DESCRIPTION

Diltiazem hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H) one, 3-(acetyloxy)-5-[2-(dimethylamino) ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride,(+)-cis-. Its molecular formula is C₂₂H₂₆N₂O₄S HCl and its molecular weight is 450.98. Its structural formula is as follows:

Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol, and chloroform.

Diltiazem hydrochloride extended-release capsules USP (once daily dosage) contain multiple units of diltiazem HCl extended-release 60 mg, resulting in 120 mg, 180 mg, or 240 mg dosage strengths allowing for the controlled release of diltiazem hydrochloride over a 24-hour period.

Inactive Ingredients: Diltiazem hydrochloride extended-release capsules USP (Once-a-day dosage) also contain acetyltributyl citrate, lactose (anhydrous), hydroxypropyl cellulose, hypromellose 2208, hydroxypropyl methylcellulose phthalate, magnesium stearate, colloidal silicon dioxide, dibasic sodium phosphate, talc, gelatin, black iron oxide, D & C Yellow # 10 aluminum lake, FD & C blue # 1 aluminum lake, FD & C blue # 2 aluminum lake, FD & C red # 40 aluminum lake, and titanium dioxide. The 180 mg and 240 mg dosage forms also contain yellow iron oxide.

This product meets USP Drug Release Test 7.

For oral administration