药物信息为DONEPEZIL HYDROCHLORIDE TABLETS73207321Rx only (Teva Pharmaceuticals USA): DESCRIPTION

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  • Donepezil hydrochloride is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as (±)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride. Donepezil hydrochloride is commonly referred to in the pharmacological literature as E2020. Donepezil hydrochloride is a white powder and is freely soluble in water, soluble in chloroform, sparingly soluble in glacial acetic acid and in ethanol, slightly soluble in acetonitrile, very slightly soluble in ethyl acetate and insoluble in n-hexane.

    C24H29NO3HCl M.W. 415.96

    Donepezil hydrochloride is available for oral administration in film-coated tablets containing 5 or 10 mg of donepezil hydrochloride. Inactive ingredients are hypromellose, lactose, lactose anhydrous, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol-part. hydrolyzed, pregelatinized starch, talc, and titanium dioxide. Additionally, 10 mg tablets contain iron oxide yellow.

  • Drug Information Provided by National Library of Medicine (NLM).
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