药物信息为Levalbuterol Hydrochloride (Mylan Pharmaceuticals Inc.): DESCRIPTION

Levalbuterol Inhalation Solution, USP is a sterile, clear, colorless, preservative-free solution of the hydrochloride salt of levalbuterol, the (R)-enantiomer of the drug substance racemic albuterol. Levalbuterol HCl is a relatively selective beta₂-adrenergic receptor agonist (see CLINICAL PHARMACOLOGY). The chemical name for levalbuterol HCl is (R)-a¹-[[(1,1-dimethylethyl) amino]methyl]-4-hydroxy-1,3-benzenedimethanol hydrochloride, and its established chemical structure is as follows:

The molecular weight of levalbuterol HCl is 275.8, and its molecular formula is C₁₃H₂₁NO₃·HCl. It is a white to off-white, crystalline solid, with a melting point of approximately 187°C and solubility of approximately 180 mg/mL in water.

Levalbuterol HCl is the USAN modified name for (R)-albuterol HCl in the United States.

Levalbuterol Inhalation Solution, USP, Concentrate is supplied in 0.5 mL individually-wrapped unit-dose vials and should be diluted with sterile normal saline before administration by nebulization. Each 0.5 mL unit-dose vial contains 1.25 mg/0.5 mL (0.25%) of levalbuterol HCl, USP (as 1.44 mg of levalbuterol HCl), sodium chloride, USP to adjust tonicity and sulfuric acid NF to adjust the pH to 4.0 (3.3 to 4.5).