药物信息为MAXALT (RIZATRIPTAN BENZOATE) TABLETSMAXALT-MLT (RIZATRIPTAN BENZOATE) ORALLY DISINTEGRATING TABLETS (Merck & Co., Inc.): DESCRIPTION

MAXALT

Registered trademark of MERCK & CO., Inc. COPYRIGHT © 1998, 2006 MERCK & CO., Inc. All rights reserved

Rizatriptan benzoate is described chemically as: N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H -indole-3-ethanamine monobenzoate and its structural formula is:

Its empirical formula is C₁₅H₁₉N₅•C₇H₆O₂, representing a molecular weight of the free base of 269.4. Rizatriptan benzoate is a white to off-white, crystalline solid that is soluble in water at about 42 mg per mL (expressed as free base) at 25°C.

MAXALT Tablets and MAXALT-MLT Orally Disintegrating Tablets are available for oral administration in strengths of 5 and 10 mg (corresponding to 7.265 mg or 14.53 mg of the benzoate salt, respectively). Each compressed tablet contains the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, ferric oxide (red), and magnesium stearate.

Each lyophilized orally disintegrating tablet contains the following inactive ingredients: gelatin, mannitol, glycine, aspartame, and peppermint flavor.