药物信息为MAXZIDE-25 (Mylan Pharmaceuticals Inc.): DESCRIPTION

MAXZIDE^® (triamterene and hydrochlorothiazide) combines triamterene, a potassium-conserving diuretic, with the natriuretic agent, hydrochlorothiazide.

Each MAXZIDE^® tablet contains:

Triamterene, USP ............................................................................... 75 mgHydrochlorothiazide, USP .................................................................. 50 mg

Each MAXZIDE^®-25 MG tablet contains:

Triamterene, USP ................................................................................ 37.5 mgHydrochlorothiazide, USP .................................................................. 25 mg

MAXZIDE^® and MAXZIDE^®-25 MG tablets for oral administration contain the following inactive ingredients: Colloidal Silicon Dioxide, Croscarmellose Sodium, Magnesium Stearate, Microcrystalline Cellulose, Powdered Cellulose, Sodium Lauryl Sulfate and D&C Yellow #10. MAXZIDE^®-25 MG tablets also contain FD&C Blue #1.

Triamterene is 2,4,7-triamino-6-phenylpteridine. Triamterene is practically insoluble in water, benzene, chloroform, ether and dilute alkali hydroxides. It is soluble in formic acid and sparingly soluble in methoxyethanol. Triamterene is very slightly soluble in acetic acid, alcohol and dilute mineral acids. Its molecular weight is 253.27. Its structural formula is:

Hydrochlorothiazide is 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Hydrochlorothiazide is slightly soluble in water and freely soluble in sodium hydroxide solution, n-butylamine and dimethylformamide. It is sparingly soluble in methanol and insoluble in ether, chloroform and dilute mineral acids. Its molecular weight is 297.73. Its structural formula is: