药物信息为Mykrox Tablets (metolazone tablets, USP) (Celltech Pharmaceuticals, Inc.): DESCRIPTION

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  • MYKROX Tablets (metolazone tablets, USP) for oral administration contain ½ mg of metolazone, USP, a diuretic/saluretic/antihypertensive drug of the quinazoline class.

    Metolazone has the molecular formula C16H16ClN3O3S, the chemical name 7-chloro-1, 2, 3, 4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, and a molecular weight of 365.83. The structural formula is:

    Metolazone is only sparingly soluble in water, but more soluble in plasma, blood, alkali, and organic solvents.

    Inactive Ingredients: Dibasic calcium phosphate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate.

  • Drug Information Provided by National Library of Medicine (NLM).
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