药物信息为ONDANSETRON Oral Solution, USP (Roxane Laboratories, Inc): DESCRIPTION

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  • The active ingredient in Ondansetron Oral Solution, USP is ondansetron hydrochloride (HCl) as the dihydrate, the racemic form of ondansetron and a selective blocking agent of the serotonin 5-HT3 receptor type. Chemically it is (±) 1, 2, 3, 9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl) methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate. It has the following structural formula:

    The molecular formula is C18H19N3O•HCl•2H2O, representing a molecular weight of 365.9. Ondansetron HCl dihydrate is a white to off-white powder that is soluble in water and normal saline.

    Each 5 mL of Ondansetron Oral Solution, USP contains 5 mg of ondansetron HCI dihydrate equivalent to 4 mg of ondansetron. Ondansetron Oral Solution, USP contains the inactive ingredients citric acid anhydrous, glycerin, saccharin sodium, sodium benzoate, sodium citrate, and strawberry flavor.

  • Drug Information Provided by National Library of Medicine (NLM).
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