药物信息为ProcalAmine (3% Amino Acid and 3% Glycerin Injection with Electrolytes) (B. Braun Medical Inc.): DESCRIPTION

ProcalAmine (3% Amino Acid and 3% Glycerin Injection with Electrolytes) is a sterile, nonpyrogenic, moderately hypertonic intravenous injection containing crystalline amino acids, a nonprotein energy substrate and maintenance electrolytes. A 1000 mL unit provides a total of 29 g of protein equivalent (4.6 g N) and 130 nonprotein calories.

All amino acids designated USP are the "L"-isomer with the exception of Glycine USP which does not have an isomer.

Each 100 mL contains:Nonprotein energy source:Glycerin USP (glycerol) .............................................................................. 3.0 g

Essential amino acidsIsoleucine USP .......................................................................................... 0.21 gLeucine USP ............................................................................................. 0.27 gLysine ....................................................................................................... 0.22 g (added as Lysine Acetate USP ................................................................ 0.31 g) Methionine USP ........................................................................................ 0.16 gPhenylalanine USP .................................................................................... 0.17 gThreonine USP .......................................................................................... 0.12 gTryptophan USP ...................................................................................... 0.046 gValine USP ................................................................................................ 0.20 g

Nonessential amino acidsAlanine USP .............................................................................................. 0.21 gGlycine USP .............................................................................................. 0.42 gArginine USP ............................................................................................. 0.29 gHistidine USP............................................................................................ 0.085 gProline USP ............................................................................................... 0.34 gSerine USP ................................................................................................ 0.18 gCysteine ...................................................................................................<0.014 g (as Cysteine HCl•H₂O USP ...................................................................<0.020 g) Sodium Acetate•3H₂O USP........................................................................ 0.20 gMagnesium Acetate•4H₂O......................................................................... 0.054 gCalcium Acetate•H₂O ............................................................................... 0.026 gSodium Chloride USP ................................................................................. 0.12 gPotassium Chloride USP.............................................................................. 0.15 gPhosphoric Acid NF ................................................................................. 0.041 gPotassium Metabisulfite NF (as an antioxidant) ............................................<0.05 gWater for Injection USP .................................................................................... qs

pH adjusted with Glacial Acetic Acid USPpH: 6.8 (6.5–7.0), Calculated Osmolarity: 735 mOsmol/literConcentration of Electrolytes (mEq/liter): Sodium 35; Potassium 24.5; Calcium 3Magnesium 5; Chloride 41; Phosphate (HPO ) 73.5 mmole/liter; 10.9 mg% P; Acetate 47Acetate is provided as inorganic acetate salts (23 mEq/liter), acetic acid (9 mEq/liter), and lysine acetate (15 mEq/liter). It is thought that acetate from lysine acetate and acetic acid, under the conditions of parenteral nutrition does not impact net acid/base balance when renal and respiratory functions are normal. Clinical experience seems to support this thinking, although confirmatory experimental evidence is not available.