药物信息为TEMOVATE (clobetasol propionate scalp application) Scalp Application, 0.05% (PharmaDerm , A division of Nycomed US Inc.): DESCRIPTION

TEMOVATE^® (clobetasol propionate scalp application) Scalp Application, 0.05% contains the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Chemically, clobetasol propionate is (11ß,16ß)-21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy) pregna-1, 4-diene-3,20-dione, and it has the following structural formula:

Clobetasol propionate has the molecular formula C₂₅H₃₂CIFO₅ and a molecular weight of 467. It is a white to cream-colored crystalline powder insoluble in water.

TEMOVATE^® Scalp Application contains clobetasol propionate 0.5 mg/g in a base of purified water, isopropyl alcohol (39.3%), carbomer 934R and sodium hydroxide.