药物信息为Tobraflex (Alcon Pharmaceuticals): DESCRIPTION

Tobraflex™ (tobramycin and fluorometholone acetate ophthalmic suspension, USP) is a sterile, multiple dose antibiotic and steroid combination for topical ophthalmic use. The chemical structures for tobramycin and fluorometholone acetate are presented below:

Tobramycin Empirical Formula: C₁₈H₃₇N₅O₉ Chemical Name: O-3-Amino-3-deoxy-α-D-glucopyranosyl- (1->4) O-[2,6-diamino-2,3,6-trideoxy- α-D-ribo-hexopyranosyl-(1->6)]-2- deoxy-L-streptamine

Fluorometholone Acetate Empirical Formula: C₂₄H₃₁FO₅ Chemical Name: 9-Fluoro-11β, 17-dihydroxy-6α- methylpregna-1,4-diene-3,20- dione 17-acetate

Each mL contains: Active: Tobramycin 0.3% (3 mg) and Fluorometholone Acetate 0.1% (1 mg).

Preservative: Benzalkonium Chloride 0.01%. Inactive: Tyloxapol, Edetate Disodium, Sodium Chloride, Hydroxyethyl Cellulose, Hydrochloric Acid and Sodium Hydroxide (to adjust pH), Purified Water. The pH range is 6.0 -7.0. DM-00