药物信息为TRIAMTERENE/HYDROCHLOROTHIAZIDECAPSULES, USP37.5 MG/25 MG (BARR LABORATORIES, INC.): ADVERSE REACTIONS

Adverse effects are listed in decreasing order of frequency; however, the most serious adverse effects are listed first regardless of frequency. The serious adverse effects associated with triamterene/hydrochlorothiazide capsules have commonly occurred in less than 0.1% of patients treated with this product.

anaphylaxis, rash, urticaria, photosensitivity.

arrhythmia, postural hypotension.

diabetes mellitus, hyperkalemia, hyperglycemia, glycosuria, hyperuricemia, hypokalemia, hyponatremia, acidosis, hypochloremia.

jaundice and/or liver enzyme abnormalities, pancreatitis, nausea and vomiting, diarrhea, constipation, abdominal pain.

acute renal failure (one case of irreversible renal failure has been reported), interstitial nephritis, renal stones composed primarily of triamterene, elevated BUN and serum creatinine, abnormal urinary sediment.

leukopenia, thrombocytopenia and purpura, megaloblastic anemia.

muscle cramps.

weakness, fatigue, dizziness, headache, dry mouth.

impotence, sialadenitis. Thiazides alone have been shown to cause the following additional adverse reactions:

paresthesias, vertigo.

xanthopsia, transient blurred vision.

allergic pneumonitis, pulmonary edema, respiratory distress.

necrotizing vasculitis, exacerbation of lupus.

aplastic anemia, agranulocytosis, hemolytic anemia.

thrombocytopenia and pancreatitis — rarely, in newborns whose mothers have received thiazides during pregnancy.