药物信息为URSODIOL CAPSULES, USP9380Rx only (TEVA Pharmaceuticals USA Inc): OVERDOSAGE
- CLINICAL PHARMACOLOGY
- INDICATIONS AND USAGE
- ADVERSE REACTIONS
- HOW SUPPLIED
- 外部链接相关的URSODIOL CAPSULES, USP9380Rx only (TEVA Pharmaceuticals USA Inc)
Neither accidental nor intentional overdosing with ursodiol has been reported. Doses of ursodiol in the range of 16 to 20 mg/kg/day have been tolerated for 6 to 37 months without symptoms by 7 patients. The LD50 for ursodiol in rats is over 5000 mg/kg given over 7 to 10 days and over 7500 mg/kg for mice. The most likely manifestation of severe overdose with ursodiol would probably be diarrhea, which should be treated symptomatically.
- Drug Information Provided by National Library of Medicine (NLM).