药物信息为Vagifem (estradiol vaginal tablets) Initial U.S. Approval: 1999 (Novo Nordisk): 4 CONTRAINDICATIONS

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  • Vagifem should not be used in women with any of the following conditions:

    • Undiagnosed abnormal genital bleeding
    • Known, suspected, or history of breast cancer
    • Known or suspected estrogen-dependent neoplasia
    • Active deep vein thrombosis, pulmonary embolism or history of these conditions
    • Active arterial thromboembolic disease (for example, stroke, and myocardial infarction), or a history of these conditions
    • Known liver dysfunction or disease
    • Known or suspected pregnancy
  • Drug Information Provided by National Library of Medicine (NLM).
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